HMGB1 is released from necrotic cells or activated macrophages / dendritic cells. Extracellular HMGB1 acts as a DAMP molecule, a SASP component, or an immunosuppressive molecule. It associates with various pathologies such as cancer, sepsis, arteriosclerosis, chronic rheumatoid arthritis and nephritis.

arigo is the global leader of HMGB1 products and offers protein, neutralizing antibody , and ELISA kits to facilitate the functional studies of extracellular HMGB1.

Protein & Antibody

HMGB1 protein (ARG70220)
● Works on human and mouse cells

HMGB1 antibody [SQab1711] (ARG65863)
● Good for ELISA, FACS, ICC/IF, IHC-P, WB 

Neutralizing antibody

HMGB1 Neutralizing antibody [SQab20175] (ARG66714)
● Mouse mAb

Referenced ELISA Kits

Human HMGB1 ELISA Kit (ARG81185)
Mouse/Rat HMGB1 ELISA Kit (ARG81310)
Serum HMGB1 ELISA Kit (ARG81351)

● Suitable for plasma, serum, cell culture supernatant, and cell/tissue lysate

● HMGB1-specific
● Easy and fast process

Extracellular HMGB1 poster

HMGB1 products

Simplify ELISA analysis by GainData